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Without insurance, both can be expensive, so affordability and approval are often part of the decision process
One research paper examined how the costs of tirzepatide (the active ingredient in Mounjaro) would compare to semaglutide (the active ingredient in Wegovy) to lose the same amount of body weight
Evidence of efficacy for Wegovy In headline data from its landmark trial evaluating cardiovascular outcomes in obese patients released last month, Novo Nordisk announced that semaglutide 2.4mg (Wegovy) demonstrated a 20 percent reduction in major adverse cardiovascular events
When patients get a prescription for a GLP-1, they should also be offered a referral to a Registered Dietitian to support personalized, long-term healthful behavior change, and reduce the risk of poor diet quality and nutrient deficiencies
A final grade of low risk of bias, some concerns of bias and high risk of bias was attributed to each article considering the score in each section
Patients should not treat it as a proven fat-loss medication
